Organic Herbal Weight Loss Powders For Tablet / Capsule
Pharmaceutical Steroids Raw Material
Liothyronine is a form of thyroid hormone used to treat
hypothyroidism and myxedema coma. It is marketed as the sodium salt
under the brand name Cytomel (or Tertroxin in Australia).
Alias: Cytomel T3 ; 3,3',5－triiodothyronine sodium
CAS NO: 55-06-1
Einecs No: 200-223-5
Appearance: white or light yellow powder, almost tasteless.
High Purity Liothyronine sodium/Cytomel T3/3,3',5－triiodothyronine
sodium/CAS No: 55-06-1 200-223-5 Weight Loss Powders
Liothyronine is the most potent form of thyroid hormone.
Chemically, it is nearly identical to triiodothyronine (T3). As such, it acts on the body to increase the basal metabolic
rate, affect protein synthesis and increase the body's sensitivity
to catecholamines (such as adrenaline) by permissiveness. The
thyroid hormones are essential to proper development and
differentiation of all cells of the human body. These hormones also
regulate protein, fat, and carbohydrate metabolism, affecting how
human cells use energetic compounds.
In comparison to levothyroxine (T4), liothyronine has a faster onset of action as well as a shorter
biological half-life, which may be due to less plasma protein
binding to thyroxine-binding globulin and transthyretin.
Physicians can use this instead of or in addition to levothyroxine
(T4) for patients undergoing thyroid withdrawal. When a patient has
thyroid cancer or Graves' disease, ablation therapy with
radioactive iodine can be used to remove any trace thyroid tissue.
For therapy to be effective, the trace thyroid tissue must be avid
to iodine. The best method is to starve the tissue of iodine but
this can lead to hypothyroid symptoms for the patient. Withdrawal
from levothyroxine can be done but it takes six weeks of withdrawal
for the remaining thyroid tissue to be completely starved. Six
weeks is needed owing to levothyroxine's long half life. Six weeks
can be inconvenient for the patient and delay treatment.
Liothyronine instead can be taken and withdrawn from for two weeks
to starve the thyroid tissue. This is much safer and more
convenient than levothyroxine.
|Appearance||An odorless, almost white or buff colored powder||pass|
|Solubility||1,Very slightly soluble in water||pass|
|2,slightly soluble in alcohol||pass|
|3,practically insoluble in most other organic solvents||pass|
|4,disolves in diluted aqueous sodium hydroxide solutions||Pass|
|Identificaton||a) Heat about 50 mg with a few drops of sulfuric acid in a
porcelain crucible: violet vapors of iodine are evolved.||pass|
|b)The retention time of the major peak is confirm to the RS||pass|
|Loss on Drying||Not more than 4.0%||0.46%|
C=1 in 1M HCl/EtOH 1:4
|+18 ~ +22o||＋20.9o|
|Assay(HPLC)||Not less than 95.0%||99.18%|
|Levothyroxine sodium||Not more than 5.0%||0.68%|
|Conclusion:||Up to the Standard for Export|
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